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Dataset index

Dataset index

The NCCR TransCure offers the following datasets as open source downloads:

2021

Dataset title: Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions
DOI: http://doi.org/10.5281/zenodo.5006338
Responsible group: C. Peinelt
Projects involved: 1
Article: link

Dataset title: Sub-nanometer cryo-EM density map of the human heterodimeric amino acid transporter 4F2hc-LAT2
DOI: https://www.ebi.ac.uk/pdbe/entry/emdb/EMD-11726
Responsible group: D. Fotiadis
Projects involved: 1
Article: link

Dataset title: The heavy chain 4F2hc modulates the substrate affinity and specificity of the light chains LAT1 and LAT2
DOI: https://doi.org/10.5281/zenodo.4899969 (online soon)
Responsible group: D. Fotiadis
Projects involved: 1
Article: link

Dataset title: Yeast cell-based transport assay for the functional characterization of human 4F2hc-LAT1 and ?LAT2, and LAT1 and LAT2 substrates and inhibitors
DOI: https://doi.org/10.5281/zenodo.4899964 (online soon)
Responsible group: D. Fotiadis
Projects involved: 1
Article: link

Dataset title: The solute carrier SLC16A12 is critical for creatine and guanidinoacetate handling in the kidney.
DOI: https://doi.org/10.6084/m9.figshare.c.5233718
Responsible group: D. Fuster
Projects involved: 1
Article: accepted manuscript

2020

Dataset title: The sodium/proton exchanger NHA2 regulates blood pressure through a WNK4-NCC dependent pathway in the kidney
DOI: https://zenodo.org/record/4894445#.YNrVEegzZaQ
Responsible group: H. Stahlberg
Projects involved: 1
Article: Link

Dataset title: The sodium/proton exchanger NHA2 regulates blood pressure through a WNK4-NCC dependent pathway in the kidney
DOI: https://doi.org/10.5061/dryad.08kprr51n
Responsible group: D. Fuster
Projects involved: 1
Article: Link

Dataset title: Counter-directed leucine gradient promotes amino acid transfer across the human placenta
DOI: 10.5281/zenodo.4384654
Responsible group: C. Albrecht
Projects involved: 1
Article: under review

Dataset title: Small molecule inhibitors provide insights into the relevance of LAT1 and LAT2 in materno-foetal amino acid transport
DOI: 10.1111/jcmm.15840
Responsible group: C. Albrecht
Projects involved: 1
Article (2020)

 

2019

Dataset title: 6TL2. Crystal structure of Eremococcus coleocola manganese transporter in complex with an aromatic bis-isothiourea substituted compound
DOI: 10.2210/pdb6TL2/pdb
Responsible group: R. Dutzler
Projects involved: 1
Article (2019)