Past NCCR TransCure Lectures
| Date, Place | Field | Speaker | Title | Host |
|---|---|---|---|---|
| 07.09.2022 Bern | Biology | Graham Ladds | Agonist bias at Class A/B GPCRs: Therapeutic potential at last? | M. Lochner |
| 27.06.2022 Bern | Biology | Katelyn Cook | Human Viruses Rewire Membrane Contact Sites for Pro-Viral Organelle Remodeling | W. Kukulski |
| 07.06.2022 Bern | Physiology | Rajesh Khanna | Navigating a new path to Nav1.7 for pain | H. Abriel |
| 09.05.2022 Bern | Biology | Andreas Kuhn | Essential Players in Membrane Biogenesis: Insertases and Translocases | D. Fotiadis |
| 09.03.2022 Bern | Career | Susan Gasser | NCCR TransCure Career Pathway Lecture | C. Peinelt H. Abriel |
| 25.11.2021 online | Physiology, Struct. Biology | See flyer | NCCR TransCure Mini-Symposium: "A trip to the TRPs" | C. Peinelt |
| 02.06.2021 online | Physiology, Struct. Biology and drug design | See flyer | NCCR TransCure MiniSymposium on divalent metal transporters | R. Dutzler, C. Albrecht |
| 16.10.2020 online | Career | Johanna Havemann | Digital reputation Building in Science | NCCRs TransCure, RNA&Disease & kidney.ch |
04.05.2020 | Biology | Manuel Palacin | CANCELLED Heteromeric Amino acid Transporters: structure and disease | D. Fotiadis |
| 27.04.2020 Bern | Biology | Simon Newstead | CANCELLED Peptides and protons: How pH gradients link transport and trafficking in the cell | D. Fotiadis |
| 03.04.2020 Bern | Career | Johanna Havemann | CANCELLED The academic internet: publishing, networking and presenting yourself online. | Access2persepctives |
| 02.04.2020 Bern | Biology | Graham Ladds | CANCELLED Factors influencing family B GPCRs: RAMPing it up | M. Lochner |
| 27.02.2020 Bern | Drug Design | Dominique Soldati-Favre | The road to malaria control and elimination in 3D: Discover, Develop, Deliver | H. Abriel |
| 20.01.2020 Bern | Physiology | Ilaria Rivolta | KCNT1 channel: let’s pick up the Slack! | H. Abriel |
| 06.11.2019 Bern | Physiology | Rose Dixon | GPCR regulated CaV1.2 channel trafficking tunes cardiac EC-coupling | H. Abriel |
| 28.10.2019 Bern | Biology | Don Benjamin | Dual inhibition of MCT1 and MCT4 by syrosingopine as a treatment modality for cancer | D. Fotiadis |
| 11.10.2019 Bern | Physiology | Ardem Patapoutian | Piezo channels in mechanotransduction: sensory biology to disease | C. Peinelt |
| 08.10.2019 Bern | Physiology | Fayal Abderemane-Ali | Ion channel modulation by calmodulin: a view of the starting and ending points | H. Abriel |
| 03.10.2019 Bern | Physiology | Stefan Feske | CRAC channels in immunity to infection and autoimmunity | C. Peinelt |
| 30.09.2019 Bern | Biology | Ramona Schlesinger | Proton translocations in Channelrhodopsin-1 from Clamydomonas augustae | D. Fotiadis |
| 12.08.2019 Bern | Physiology | Benjamin Lüscher | Regulation of the Na+-HCO3- Cotransporters NBCe1-B and the Cl- Channel CFTR by the ER-PM Tether Protein Extended Synaptotagmin 3 | C. Peinelt |
| 12.08.2019 Bern | Physiology | Indu Ambudkar | STIM2 co-ordinates assembly and function of Orai1/STIM1 in specialized ER-PM junctions. | C. Peinelt |
| 13.06.2019 Zürich | Biology | Hendrik van Veen | Energy coupling in ABC exporters | K. Locher |
| 09.05.2019 Zürich | Biology | Cristina Paulino | The KdpFABC Complex: What Happens When a P-type ATPase Hijacks an Ion Channel | R. Dutzler |
| 09.05.2019 Bern | Drug Design | Mauro Maccarrone | Endocannabinoids, Neuroinflammation and Beyond | J. Gertsch |
| 06.05.2019 Bern | Biology | Manuele Rebsamen | Functional characterization of solute carriers using omics approaches: cell growth, signaling and death. | H. Abriel |
| 29.04.2019 Bern | Biology | Anderas Kuhn | Folding and stepwise insertion of bacterial membrane proteins | D. Fotiadis |
| 01.04.2019 Bern | Biology | Vera Regitz-Zagrosek | Sex and gender in basic and translational cardiovascular research | |
| 25.03.2019 Bern | Biology | Camilo Perez | Structure and Mechanism of membrane proteins involved in lipids translocation | D. Fotiadis |
22.03.2019 Bern | Drug Design | Nicolas Winnsinger | PNA-encoded molecules to program assemblies and reaction in chemical biology | J.-L. Reymond |
| 15.03.2019 Bern | Drug Design | Karl-Heinz Altmann | The Chemistry and Biology of Dactylolide and Zampanolide | J.-L. Reymond |
| 28.01.29 Bern | Physiology | Jan Loffing | The renal distal convoluted tubule: Key player in ion homeostasis and blood pressure control | H. Abriel |
14.01.19 | Biology | Gail Robertson | Cotranslational Regulation of Excitability in the Heart | H. Abriel |
| 22.11.18 Bern | Physiology | Anna Boccaccio | Phospholipid scrambling activity by TMEM16E/ANO5: opposite effects of mutations causing bone dysplasia and muscular dystrophy | L. Ozhathil |
| 14.09.18 Zurich | Biology | Alessio Accardi | Mechanism of Ca2+-dependent membrane remodeling by a TMEM16 phospholipid scramblase | R. Dutzler |
| 13.09.18 Bern | Drug Design | Scott Snyder | Strategies and Tactics for the Rapid Synthesis of Molecular Complexity | J.-L. Reymond |
| 13.09.18 Bern | Drug Design | Nicolas Foloppe | Characterising the unbound state of drug-like compounds: implications for molecular recognition | J.-L. Reymond |
| 12.09.18 Bern | Biology | Pascale Gaudet | Biocuration: A cornerstone for research | H. Abriel |
| 17.07.18 Bern | Physiology | Ryuji Inoue | A theoretical approach to investigating the arrhythmogenicity of TRPM4 channel. | H. Abriel |
| 20.06.2018 Bern | Drug design | Craig Crews | PROTAC-mediated Protein Degradation: A New Therapeutic Modality | M. Lochner |
| 06.06.2018 Bern | Physiology | L. Delemotte | Mechanisms of electromechanical coupling in voltage-gated ion channels | H. Abriel |
| 18.04.2018 Bern | Physiology | P. Lory | Deciphering pathogenic mechanisms underlying human calcium channelopathies | J.-S. Rougier |
| 12.04.2018 Bern | Biology | Amanda Sferruzzi-Perri | The fight for resources during pregnancy: a role for IGF2 signalling? | C. Albrecht |
| 20.03.2018 Zürich | Biology | Vanessa Ruta | Mechanisms of Adaptive Behavior, from Receptors to Circuits | R. Dutzler |
| 07.03.2018 Bern | Biology | Mitchell Knutson | ZIP (SLC39A) transporters and iron homeostasis | C. Albrecht |
| 18.01.2018 Zürich | Biology | Nicholas Reyes | Allosteric inhibition and Cholesterol regulation of a human excitatory amino acid transporter | R. Dutzler |
| 11.12.2017 Bern | Biology | Christian Löw | Structural insights into nutrient uptake transporters | D. Fotiadis |
| 27.11.2017 Bern | Biology | Wanda Kukulski | Linking architecture and function of cellular membranes by correlative microscopy | D. Fotiadis |
| 23.11.2017 Bern | Physiology | Olaf Pongs | The ion channel TRPM4 in cardiac conduction disease - wrestling with SUMO | C. Peinelt |
| 09.11.2017 Bern | Physiology | Milena Bellin | Cardiomyocytes from human pluripotent stem cells for studying cardiac arrhythmia and for drug screening | H. Abriel |
| 01.11.2017 Bern | Physiology | Paula Nunes-Hasler | Connecting the dots: Exploring ER-phagosome membrane contact sites during antigen cross-presentation | C. Peinelt |
| 25.10.2017 Bern | Drug Design | Dennis Dougherty | Chemistry in the Brain: Understanding the Nicotine Receptor | J.-L. Reymond |
| 23.10.2017 Bern | Biology | Cesare Indivieri | An intriguing example of amino acid transporter, LAT1: The "LATest" findings on structure/function relationships and relevance to human health | D. Fotiadis |
| 14.09.2017 Bern | Biology | Laura Soucek | Targeting the undruggable: inhibiting Myc in cancer | R.-P. Charles |
| 08.09.2017 Bern | Drug Design | Christopher Fowler | The endocannabinoid system - cellular regulation and dysfunction in cancer | J. Gertsch |
| 21.06.2017 Bern | Physiology | Armagan Kocer | Understanding and controlling the functioning of ion channels: from physiology to nanomedicine | C. Peinelt |
| 22.05.2017 Bern | Biology | Thomas Stockner | Neurotransmitter transporters under the microscope: ligands, structures, and function | D. Fotiadis |
| 10.04.2017 Bern | Biology | Yoel Sadovsky | Novel antiviral Signals at the Maternal-Placental-Fetal Communication Interface | C. Albrecht |
| 30.03.2017 Bern | Drug Design | Vittorio Limongelli | Estimating Ligand/Protein and Protein/Protein Binding Free Energy and Kinetics | H. Abriel |
| 24.03.2017 Bern | Special Lecture in Entrepreneurship | Mark Wilson | Don't let the tail wag the dog!" | NCCRs TransCure, RNA&Disease, PlanetS |
| 01.03.2017 Zürich | Biology | Anant Menon | Molecular Mechanism of Lipid Scrambling by Opsin | R. Dutzler |
| 23.02.2017 Bern | Physiology | Laura Lucia Prieto Godino | Tales of an ionotropic olfactory receptor: The surprising evolutionary trajectory of a pseudogene” | H. Abriel |
| 19.01.2017 Bern | Biology | Patrick Mehlen | The Dependence Receptor Paradigm: When a bizarre cell biology pathway meets clinic | R.-P. Charles |
| 25.11.2016 Bern | Physiology | Jutta Engel | What the ear and auditory pathway tell us about the functions of alpha2delta Ca2+ channel subunits | C. Peinelt |
| 18.11.2016 Bern | Physiology | Bin Qu | When immune killer cells meet their targets | C. Peinelt |
| 08.11.2016 Zürich | Biology | Dirk Slotboom | Mechanisms of cobalamin uptake | K. Locher |
| 21.10.2016 Bern | Physiology | Jeanne Nerbonne | Intracellular Fibroblast Growth Factors (iFGFs): Novel Regulators of Neuronal Excitability | H. Abriel |
| 22.09.2016 Bern | Biology | Uwe Schlattner | Mitochondrial NM23-4/OPA1 complexes in membrane dynamics and cardiolipin-supported mitophagy signaling | M. Hediger |
| 14.09.2016 Bern | Biology | Avner Schlessinger | Structure-based drug discovery for cancer metabolism transporters | D. Fotiadis |
| 04.07.2016 Bern | Physiology | Jonathan Lederer | Tugging at the heartstrings: Surprising heart discoveries | H. Abriel |
| 20.06.2016 Bern | Physiology | A. Meredith | Big Time for BK: Mechanisms of Circadian Rhythm in Neuronal Activity | H. Abriel |
| 09.05.2016 Bern | Biology | Klaas M. Pos | How multidrug efflux pump AcrB recognizes multiple drugs | D. Fotiadis |
21.03.2016 | Physiology | Will Brackenbury | Voltage-gated sodium channels: novel targets for cancer therapy? | H. Abriel |
| 15.03.2016 Zürich | Biology | Richard Callaghan | Inching closer to a molecular mechanism for multidrug transport by P-glycoprotein? | K. Locher |
| 29.01.2016 Zürich | Biology | Christopher Miller | A weird ion channel for a weird ion: Fluoride resistance in microorganisms | R. Dutzler |
| 07.12.2015 Bern | Biology | Raimund Dutzler | Structural basis for cellular iron uptake by the SLC11/NRAMP family of transport proteins | Hugues Abriel |
| 20.11.2015 Bern | Physiology | Hans Beat Hadorn | Cystic fibrosis: Transport of anions in different organs, clinical observations, pathophysiology and therapy | Matthias Hediger |
| 13.11.2015 Bern | Biology | Maria-Clemencia Hernandez | The GABAA 5 receptor subtype: A target for novel medicines | Jürg Gertsch |
| 11.11.2015 Bern | Drug Design | Cristina Nevado | Challenging Targets, Unique Binding Modes: Novel Strategies Against Cancer | Jean-Louis Reymond |
| 28.09.2015 Bern | Physiology | Nicole Schmitt | Role of the potassium channel Kv7.1 in insulin secretion | Hugues Abriel |
| 22.09.2015 Bern | Physiology | Rajesh Thakker | New insights in calcium regulation: G-protein coupled receptor (GPCR) signalling and trafficking | Daniel Fuster |
| 22.09.2015 Bern | Physiology | Jean-Pierre Montani | Pathogenesis of arterial hypertension - Guytons hypothesis revisited | Daniel Fuster |
| 14.09.2015 Bern | Biology | Andrea Brüggemann | New technologies to study ion channels and transporters | Hugues Abriel |
| 18.06.2015 Bern | Biology | Henriette Meyer zu Schwabedissen | The interplay of nuclear receptors and drug transporters – and beyond | Sven Rottenberg |
| 10.06.2015 Bern | Physiology | Orson Moe | Novel insights into renal acid-base transport in the metabolic syndrome | Daniel Fuster |
| 04.06.2015 Bern | Biology | Jana Kusch | Patch-clamp fluorometry – Binding and gating in ligand-gated ion channels | Jürg Gerstch |
| 03.06.2015 Zürich | Biology | David Drew | Establishing the molecular mechanisms of solute-carrier (SLC) transporters: from snapshots to movies | Kaspar Locher |
| 28.05.2015 Zürich | Drug Design | Karl-Heinz Altmann | Total synthesis and biological exploration of macrocyclic natural products | Jean-Louis Reymond |
| 20.05.2015 Bern | Drug Design | Wolfgang Jahnke | Contributions of Structural Biology to Drug Discovery | Jean-Louis Reymond |
| 11.05.2015 Bern | Biology | Manuel Palacin | Heteromeric amino acid transporters: animal and structural models | Dimitrios Fotiadis |
| 27.03.2015 Bern | Drug Design | Anna Hirsch | Exploring lead-identification strategies | Jean-Louis Reymond |
| 26.03.2015£ Bern | Drug Design | Gisbert Schneider | From models to molecules by design | Jean-Louis Reymond |
| 18.03.2015 Bern | Drug Design | Holger Gohlke | Analyzing biomacromolecules as frameworks: How (changes in) protein flexibility influence(s) molecular recognition | Jean-Louis Reymond |
| 11.03.2015 Bern | Drug Design | Luc Patiny | Swiss-knife for chemists in the web-browser | Jean-Louis Reymond |
| 17.11.2014 Bern | -- | Philippe Krebs | Peptide transport (SLC15A4) and antigen processing | Matthias Hediger |
| 10.11.2014 Bern | -- | Martin McMahon | The role of oncogenic BRAF in tumor initiation, cancer progression and pathway-targeted therapy | Roch-Philippe Charles |
| 30.07.2014 Bern | -- | Donald Hilgemann | Massive endocytosis, mitochondrial signaling & the sodium pump | Matthias Hediger |
| 23.05.2014 Bern | -- | Etienne Meylan | Signaling and metabolic pathways in non-small cell lung cancer | Roch-Philippe Charles |
28.04.2014 | -- | Baruch Kanner | Mechanism of Sodium-Coupled Neurotransmitter Transport | Dimitrios Fotiadis |
| 18.09.2013 Zürich | -- | Lutz Schmitt | The Initial Steps in a Type I Secretion System | Kaspar Locher |
| 02.04.2013 Bern | -- | Norman Saunders | Transport Mechanisms in the developing choroid plexus | Matthias Hediger |
| 10.07.2012 Bern | -- | Krzysztof Palczewski | Mendelian Genetics & Complex Genetic Traits that Cause Blinding Diseases: From Structures to Drugs | Dimitrios Fotiadis |
