Genetics of membrane transporters
|Carmeli Cristian||Postdoctoral Fellow|
|Ghobril Jean-Pierre||Postdoctoral Fellow|
The aim of this project is to position TransCure’s transporter/channel targets in a broader context and identify opportunities to link its basic scientific achievements to potential future translational applications.
Through access to different population-based cohorts and publicly available databases, (1) the inventory of common and rare variants in the genes of specific interest to NCCR TransCure and (2) the association of these variants with human traits is analyzed. For different cohorts, there is a wealth of phenotypic information available making the association to genetic variants an attractive and promising approach to identify options for future translational applications.