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Past lectures

Past NCCR TransCure Lectures

Date, PlaceFieldSpeakerTitleHost
22.11.18PhysiologyAnna BoccaccioPhospholipid scrambling activity by TMEM16E/ANO5: opposite effects of mutations causing bone dysplasia and muscular dystrophyL. Ozhathil
14.09.18
Zurich
BiologyAlessio AccardiMechanism of Ca2+-dependent membrane remodeling by a TMEM16 phospholipid scramblaseR. Dutzler
13.09.18
Bern
Drug DesignScott SnyderStrategies and Tactics for the Rapid Synthesis of Molecular ComplexityJ.-L. Reymond
13.09.18
Bern 
Drug DesignNicolas FoloppeCharacterising the unbound state of drug-like compounds: implications for molecular recognitionJ.-L. Reymond
12.09.18
Bern
BiologyPascale GaudetBiocuration: A cornerstone for research H. Abriel
17.07.18
Bern
PhysiologyRyuji Inoue

A theoretical approach to investigating the arrhythmogenicity of TRPM4 channel.

H. Abriel
20.06.2018
Bern
Drug designCraig CrewsPROTAC-mediated Protein Degradation: A New Therapeutic ModalityM. Lochner
06.06.2018
Bern
PhysiologyL. Delemotte

Mechanisms of electromechanical coupling in voltage-gated ion channels

H. Abriel
18.04.2018
Bern
PhysiologyP. LoryDeciphering pathogenic mechanisms underlying human calcium channelopathiesJ.-S. Rougier
12.04.2018
Bern
BiologyAmanda Sferruzzi-Perri

The fight for resources during pregnancy: a role for IGF2 signalling?

C. Albrecht
20.03.2018
Zürich
BiologyVanessa RutaMechanisms of Adaptive Behavior, from Receptors to CircuitsR. Dutzler
07.03.2018
Bern
BiologyMitchell KnutsonZIP (SLC39A) transporters and iron homeostasisC. Albrecht
18.01.2018
Zürich
BiologyNicholas ReyesAllosteric inhibition and Cholesterol regulation of a human excitatory amino acid transporterR. Dutzler
11.12.2017
Bern
BiologyChristian LöwStructural insights into nutrient uptake transportersD. Fotiadis
27.11.2017
Bern
BiologyWanda KukulskiLinking architecture and function of cellular membranes by correlative microscopyD. Fotiadis
23.11.2017
Bern
PhysiologyOlaf PongsThe ion channel TRPM4 in cardiac conduction disease - wrestling with SUMOC. Peinelt
09.11.2017
Bern
PhysiologyMilena BellinCardiomyocytes from human pluripotent stem cells for studying cardiac arrhythmia and for drug screeningH. Abriel
01.11.2017
Bern
PhysiologyPaula Nunes-HaslerConnecting the dots: Exploring ER-phagosome membrane contact sites during antigen cross-presentationC. Peinelt
25.10.2017
Bern
Drug DesignDennis DoughertyChemistry in the Brain:  Understanding the Nicotine ReceptorJ.-L. Reymond
23.10.2017
Bern
BiologyCesare IndivieriAn intriguing example of amino acid transporter, LAT1: The "LATest" findings on structure/function relationships and relevance to human healthD. Fotiadis
14.09.2017
Bern 
BiologyLaura Soucek

Targeting the undruggable: inhibiting Myc in cancer

R.-P. Charles
08.09.2017
Bern
Drug DesignChristopher Fowler

The endocannabinoid system - cellular regulation and dysfunction in cancer

J. Gertsch
21.06.2017
Bern
PhysiologyArmagan KocerUnderstanding and controlling the functioning of ion channels: from physiology to nanomedicineC. Peinelt
22.05.2017
Bern
BiologyThomas StocknerNeurotransmitter transporters under the microscope: ligands, structures, and function D. Fotiadis
10.04.2017
Bern
BiologyYoel SadovskyNovel antiviral Signals at the Maternal-Placental-Fetal Communication InterfaceC. Albrecht
30.03.2017
Bern
Drug DesignVittorio LimongelliEstimating Ligand/Protein and Protein/Protein Binding Free Energy and KineticsH. Abriel
24.03.2017
Bern
Special Lecture in EntrepreneurshipMark Wilson

Don't let the tail wag the dog!"


NCCRs TransCure, RNA&Disease, PlanetS
01.03.2017
Zürich
BiologyAnant Menon

Molecular Mechanism of Lipid Scrambling by Opsin

R. Dutzler
23.02.2017
Bern
PhysiologyLaura Lucia Prieto GodinoTales of an ionotropic olfactory receptor: The surprising evolutionary trajectory of a pseudogene”H. Abriel
19.01.2017
Bern
BiologyPatrick MehlenThe Dependence Receptor Paradigm: When a bizarre cell biology pathway meets clinicR.-P. Charles
25.11.2016
Bern
PhysiologyJutta EngelWhat the ear and auditory pathway tell us about the functions of alpha2delta Ca2+ channel subunitsC. Peinelt
18.11.2016
Bern
PhysiologyBin QuWhen immune killer cells meet their targetsC. Peinelt
08.11.2016
Zürich
BiologyDirk SlotboomMechanisms of cobalamin uptakeK. Locher
21.10.2016
Bern
PhysiologyJeanne NerbonneIntracellular Fibroblast Growth Factors (iFGFs): Novel Regulators of Neuronal ExcitabilityH. Abriel
22.09.2016
Bern
BiologyUwe SchlattnerMitochondrial NM23-4/OPA1 complexes in membrane dynamics and cardiolipin-supported mitophagy signalingM. Hediger
14.09.2016
Bern
BiologyAvner SchlessingerStructure-based drug discovery for cancer metabolism transportersD. Fotiadis
04.07.2016
Bern
PhysiologyJonathan LedererTugging at the heartstrings: Surprising heart discoveriesH. Abriel
20.06.2016
Bern
PhysiologyA. MeredithBig Time for BK: Mechanisms of Circadian Rhythm in Neuronal ActivityH. Abriel
09.05.2016
Bern
BiologyKlaas M. PosHow multidrug efflux pump AcrB recognizes multiple drugsD. Fotiadis

21.03.2016
Bern

PhysiologyWill BrackenburyVoltage-gated sodium channels: novel targets for cancer therapy?H. Abriel
15.03.2016
Zürich
BiologyRichard CallaghanInching closer to a molecular mechanism for multidrug transport by P-glycoprotein?K. Locher
29.01.2016
Zürich
BiologyChristopher MillerA weird ion channel for a weird ion: Fluoride resistance in microorganismsR. Dutzler
07.12.2015
Bern
BiologyRaimund DutzlerStructural basis for cellular iron uptake by the SLC11/NRAMP family of transport proteinsHugues Abriel
20.11.2015
Bern
PhysiologyHans Beat HadornCystic fibrosis: Transport of anions in different organs, clinical observations, pathophysiology and therapyMatthias Hediger
13.11.2015
Bern
BiologyMaria-Clemencia HernandezThe GABAA 5 receptor subtype: A target for novel medicinesJürg Gertsch
11.11.2015
Bern
Drug DesignCristina NevadoChallenging Targets, Unique Binding Modes: Novel Strategies Against CancerJean-Louis Reymond
28.09.2015
Bern
PhysiologyNicole SchmittRole of the potassium channel Kv7.1 in insulin secretionHugues Abriel
22.09.2015
Bern
PhysiologyRajesh ThakkerNew insights in calcium regulation: G-protein coupled receptor (GPCR) signalling and traffickingDaniel Fuster
22.09.2015
Bern
PhysiologyJean-Pierre MontaniPathogenesis of arterial hypertension - Guytons hypothesis revisitedDaniel Fuster
14.09.2015
Bern
BiologyAndrea BrüggemannNew technologies to study ion channels and transportersHugues Abriel
18.06.2015
Bern
BiologyHenriette Meyer zu SchwabedissenThe interplay of nuclear receptors and drug transporters – and beyondSven Rottenberg
10.06.2015
Bern
PhysiologyOrson MoeNovel insights into renal acid-base transport in the metabolic syndromeDaniel Fuster
04.06.2015
Bern
BiologyJana KuschPatch-clamp fluorometry – Binding and gating in ligand-gated ion channelsJürg Gerstch
03.06.2015
Zürich
BiologyDavid DrewEstablishing the molecular mechanisms of solute-carrier (SLC) transporters: from snapshots to moviesKaspar Locher
28.05.2015
Zürich
Drug DesignKarl-Heinz AltmannTotal synthesis and biological exploration of macrocyclic natural productsJean-Louis Reymond
20.05.2015
Bern
Drug DesignWolfgang JahnkeContributions of Structural Biology to Drug DiscoveryJean-Louis Reymond
11.05.2015
Bern
BiologyManuel PalacinHeteromeric amino acid transporters: animal and structural modelsDimitrios Fotiadis
27.03.2015
Bern
Drug DesignAnna HirschExploring lead-identification strategiesJean-Louis Reymond
26.03.2015£
Bern
Drug DesignGisbert SchneiderFrom models to molecules by designJean-Louis Reymond
18.03.2015
Bern
Drug DesignHolger GohlkeAnalyzing biomacromolecules as frameworks: How (changes in) protein flexibility influence(s) molecular recognitionJean-Louis Reymond
11.03.2015
Bern
Drug DesignLuc PatinySwiss-knife for chemists in the web-browserJean-Louis Reymond
17.11.2014
Bern
--Philippe KrebsPeptide transport (SLC15A4) and antigen processingMatthias Hediger
10.11.2014
Bern
--Martin McMahonThe role of oncogenic BRAF in tumor initiation, cancer progression and pathway-targeted therapyRoch-Philippe Charles
30.07.2014 
Bern
--Donald HilgemannMassive endocytosis, mitochondrial signaling & the sodium pumpMatthias Hediger
23.05.2014
Bern
--Etienne MeylanSignaling and metabolic pathways in non-small cell lung cancerRoch-Philippe Charles

28.04.2014
Bern

--Baruch KannerMechanism of Sodium-Coupled Neurotransmitter TransportDimitrios Fotiadis
18.09.2013
Zürich
--Lutz SchmittThe Initial Steps in a Type I Secretion SystemKaspar Locher
02.04.2013
Bern
--Norman SaundersTransport Mechanisms in the developing choroid plexusMatthias Hediger 
10.07.2012
Bern
--Krzysztof PalczewskiMendelian Genetics & Complex Genetic Traits that Cause Blinding Diseases: From Structures to DrugsDimitrios Fotiadis